Jennifer Aniston is hitting back at comments made by Ohio Sen. JD Vance, now the Republican vice presidential candidate, in which he described certain politicians, including Vice President Kamala Harris as “childless cat ladies.”

Vance’s remarks to Carlson have resurfaced and gone viral in the wake of former President Donald Trump choosing Vance as his 2024 vice presidential running mate, and Harris becoming the presumptive Democratic presidential nominee.

Aniston has spoken publicly about the struggles she faced while trying to get pregnant in her late 30s and early 40s, telling Allure magazine in 2022 that she went through in-vitro fertilization and was “throwing everything” at trying to become pregnant.

Harris is a stepmom to two children, Cole Emhoff and Ella Emhoff, through her marriage to Second Gentleman Doug Emhoff.